ExperimentSubset is an R package to manage subsets of Bioconductor Experiment objects during an analysis workflow. The package boasts features such as efficient memory management and provenance tracking while keeping data redundancy at minimum. This work was led by lab member Irzam Sarfraz and was recently accepted for publication in Read more…
A study led by Neil Ganem and his graduate student Ryan Quinton was published in Nature. Genomic characteristics of tumors that have undergone whole-genome doubling (WGD) were explored and a novel vulnerability was identified in the gene KIF18A using the Broad’s Dependency Map data. KIF18A encodes a mitotic kinesin protein Read more…
Our Bayesian method for identifying and removing contamination from single cell data was recently published in Genome Biology. This work was led by Iris Yang in collaboration with Masanao Yajima. This method is available in the Celda R package.